Chasing the Moon (1922)

Dwight Locke, a blasé millionaire who has seen and done everything, gives a party for his ranch hands at a city restaurant. His fiancée, Jane Norworth, sees him there with a chorus girl and later upbraids him for not being a worker like her chemist brother Milton. When Dwight breaks a glass distillation bottle in Milton's laboratory and cuts his hand, he learns that it contains a poison that will kill in 30 days unless offset by an antidote known only to Professor Sulphite, who has sailed for Russia. Dwight takes up the chase to find the professor within the time limit, with adventures aboard horses, ships, carriages, and trains. Meanwhile, Milton discovers that the container did not contain poison and that Dwight will die if he takes the antidote, so he and Jane pursue Dwight until they find him in Spain, where the lovers are united.