The Powerpuff Girls were big at the time. Always fighting crime, beating up monsters and saving the world before their bedtime. Then after a tragic accident, everyone started blaming them for not saving their town. 19 years later, they're now grown up and moved on to new lives. Blossom is now a writer, director and producer of her failed sitcoms. Bubbles is now a singer and goes all over the world to sing copyrighted songs and she hasn't been sued yet. But Buttercup misses the good old days and fights crime behind Blossom and Bubbles' back.