Zero Punctuation occasionally makes strong sexual references including crude humor, animations referencing sex, objects reminiscent of genitalia and mentions of strange fetishes he or the main character/publisher/fanbase of a game may have.

There is a large amount of literal cartoon violence in each animation, usually involving the "imps" shown in the series' logo.

Excessive strong language is used in every video, primarily for shock value, due to Yahtzee's dark and edgy sense of humor. "Fuck", "Shit", "Asshole", "Twat", "Wanker", etc. Are the most commonly used words. "Motherfucker", "Cunt", "Cock", etc. Are used on some occasions. Some slurs have also been used.

Strong drug references, jokes about games driving him to drink, getting high off of strange substances.

Very dark sense of humour, his jokes sometimes reference dead children, can be very offensive to some, especially those who are interested in politics.