Quick Draw features a hefty amount of sexual humor and language, but there is no actual nudity. There are many scenes which take place in the local brothel, main characters who are prostitutes, and discussion of sexual acts in every episode.

Each episode features a typical dose of "western" violence including gun fights, fist fights, and blood. Characters are killed and there are plenty of depictions of dead bodies. That being said, the show does not tend to be particularly gory or graphic.

Alcohol consumption is a regular part of the show with much of the humor centering around it. Alcoholism and drunkenness is depicted often.