There are teenage crushes throughout the series and some kissing in a few episodes. There are discussions on hormones and body changes from a 14 year old perspective. Two girls talk about another girl "waking up with a chest and becoming popular" in the pilot.

In the Halloween episode Lizzie dresses as a zombie as a prank. It is done in jest, but can be scary for younger viewers.

One character uses the term "sucks" to describe a less than ideal situation.

In ''Rated Arrgh'', there's a few times where a close-up of Larry Tudgeman's face and making loud kissing sounds that might be considered as 'jumpscares' and may startle some viewers.