Blue Gender (1999)7.1 /10

Storyline:  At some point in his young life, Yuji Kaido has gained an untreatable disease and is cryogenically frozen until proper treatment is discovered. But when he wakes, Yuji finds that a mysterious race of Aliens known as Blue colonized Earth and almost extinguished the human race. Before he is attacked by them, a soldier in a mech named Marcelene rescues him to safety. Along the way, they have to adapt their plan so they can reach a new home: a place called Second Earth.