"Faggot" and "faggy" are used occasionally as a general insult (both slurs are bleeped on Adult Swim).
The N word with a hard R is rarely used.
"Shit" is uncensored in a few episodes in Season 4.
Comedic profanity.
Riley uses the word "Gay" throughout the entire series.
Some uses of retarded.
Moderate/Severe in a lot of episodes.
Faggot is used.
Dick is used.
Hell and Damn are said.
Ass is said.
Many uses of fuck, shit, bitch, ass, asshole, prick, hell, damn, crap, fuck you, skank, bitch ass, nigga, nigger, dick, cock, pussy, faggot, fag, faggy, fuck off, tits, balls, hoe, prick, whore, slut, cunt, bastard, douche, douchebag, motherfucker, son of a bitch, jackass, fatass, smartass, badass, crack, cracker, kike, dyke, queer, coon, tranny, trans, she-male, twink, cocksucker, suck my dick, spic, pollacks, homo, beaner, cum, etc.
Use of shut your bitch ass up.
Frequent strong uses of fuck, motherfucker and nigga.
Strong language throughout.
'Fuck', 'shit', and 'pussy'(until season 3) are bleeped out on TV, but 'nigga' is said regularly (except for The Itis), 'bitch' frequently, 'ho' sporadically, and others occasionally.