Sex scenes are rampant in this series that often features a variety of sexual situations. Situations have featured casual sexual relationships, sex with multiple partners, prostitution, and sexual situations such as incest, necrophilia, bestiality, and pedophilia.

Rape is a major theme during Season 3 and 4 due to a serial rapist/killer character called The Carver.

Frequent surgeries such as breast implants and penis enlargements, as well as genital reconstructive surgeries.

Sexual fetishes often become subject matter explored in the series, such as group sex. In later seasons autoerotic asphyxiation is depicted due to a main character trying it out after hearing of it from a patient.

Nudity in the series is limited to numerous male bare buttocks and brief glimpses of bare breasts with the nipples being covered.

Violence in the program, outside of surgical procedures, is also quite graphic and featured things as trivial as a scuffle to things as extreme as self-inflicted injuries, murder, rape, torture, dismemberment, necrophilia, and even castration in one episode.

Hell, damn, bitch, ass, pussy, cum, fuck, shit.

Ass, hell, damn, douche, douchebag, cum, fuck, shit, bitch, cock, cunt, dick, whore, slut, bastard, retard, penis, tits, hoe, and twat.

Shit, cum, pussy, and cock are used frequently among lesser profanity like ass. Homophobic slurs are also used.

In season 1 episode 1, female character is seen snorting line off the table.

Alcohol, tobacco, cannabis, heroin, ecstacy, meth, and prescription medication used.

Some of the killers, called The Carver, can be frightening to some people.