There may be times when sex-related topics are mentioned, but as it's a daytime show, there's no sex or nudity physically shown. There is also plenty of innuendo, especially when Philip and Holly hosted the show.
Violence & Gore
None
Unless it's occasional slapstick played for laughs, then there's none.
Profanity
Mild
There's infrequent uses of "Damn", "Hell" and "Oh My God". Also, as the programme is broadcast live, and it isn't delayed to censor profanity, guests and/or presenters may accidently use profanity of any form without censorship. The presenters are forced to apologise if so due to Ofcom rules.
Alcohol, Drugs & Smoking
Mild
Infrequent alcohol usage, especially with Phillip and Holly around. Before the change of date of the National Television Awards, it's common for the two to be drunk from the night before and act silly and uncontrollable.