A man gives oral sex to a topless pregnant woman (her breasts are briefly seen). This is the only explicitly sexual scene in the show.

Fully nudity of woman clear, genitalia hard to discern.

Several execution style murders, including stabbings, shootings, burning people alive, beatings, and a particularly disturbing scene depicting a man being crushed with a sledgehammer. All of the violence is on screen with very little editing around the details. Many other shootouts, bombings, and fights take place, almost every episode. These often end in bloody/sometimes very gory results (often with innocent victims).

Torture of prisoners, mostly by soldiers is implied, but only shown by sound and aftermath.

In a scene in the third episode, a large pig is captured and slaughtered after it is hung up by one leg. A graphic sequence of the animal's throat being cut and blood pouring into a barrel is quite visible.

Pervasive language throughout.

The plot concerns a large cocaine shipment from Mexico to Italy. Chris and some of his family members are seen smoking marijuana, presumably medicinal, for Chris' Huntington's disease. Chris is seen regularly taking a prescription medication, probably for control of his symptoms.

The show's consistently uneasy and dark atmosphere may be too intense for some viewers.