Sexual content including innuendo and partial nudity.

There are multiple scenes of disturbing violence and gore in just about every episode. If it weren't a cartoon and also played for (sick) humor, it would be rated TV-MA at a minimum.

Since the show revolves around a cursed town, it should be no surprise that there are multiple murders, at least one per episode.

Explicit words aren't used that much.

Flute has a habit of occasionally cursing by using the names of actors who have three names, e.g., he'll say "holy Julia-Louis Dreyfus!"